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_Cellular Renewal in a Bottle_
# EXOPURE BOOSTER- The Serum
Science-backed intensive serum with **18 billion stem cell–derived exosomes** and growth factors to support skin’s resilience, vitality, and renewal.
_Visibly smoother, firmer, and more radiant skin in as little as_ _**7 days.**_
MADE IN THE USA \| 30 ML. e 1.1 FL.OZ
One Time Purchase
$400.00Sale price $400.00
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## Exopure Booster with exosomes- The Serum
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- Description
- Exosomes Technology
- Benefits
- Formula
See AllSee All
**The EXOPURE Booster** is a weightless, high-concentration, fast-absorbing serum powered by **MSC-derived exosomes**— nature’s microscopic messengers that help skin look smoother, brighter, and more resilient.
- **Concentrated Power:** 18 billion MSC Exosomes that works with your skin to deliver powerful, visible results.
- **Clinically Vetted:** Dermatologist-tested, non-irritating, and non-comedogenic—won't clog pores.
- **Clean Formula:** Free from parabens, sulfates, phthalates, drying alcohol, and synthetic colors.
- **Sourced & Made in the USA:** Rigorously tested and precisely processed in the United States.
At the heart of Regenera is our **MSC-derived Exosome Technology** — advanced bioactive vesicles naturally found in the human body that act as nature’s messengers for vital cell-to-cell communication.
In skincare, these microscopic messengers help support smoother-looking texture, renewed radiance, and a healthier, more resilient appearance. Our proprietary Exopure Complex pairs these exosomes with advanced peptides and hydrating agents, creating a high-performance ritual that works in harmony with your skin.
With consistent use, the results become more visible over time — skin that looks brighter, feels stronger, and appears more youthful.
Sourced, rigorously tested, and precisely processed in the **USA**, each 30 ml bottle delivers **18 billion** exosomes for targeted skin support.
**Proven Results for a Healthier Skin**
- **Calms & Soothes:** Reduces the appearance of redness and irritation for a more comfortable, balanced complexion.
- **Hydrates & Strengthens:** Delivers deep hydration while reinforcing the skin barrier to lock in moisture and improve elasticity.
- **Smooths & Refines:** Conditions the skin for a velvety-soft texture and helps minimize the appearance of pores.
- **Visibly Rejuvenates:** Diminishes the look of fine lines and wrinkles, restoring firmness and enhancing your skin's natural radiance.
- **Protects & Defends:** Shields skin from daily environmental stressors that can accelerate aging.
Clean, Safe & Consciously Formulated
- **Dermatologist-tested** for safety and efficacy
- O **il-free and non-comedogenic**— won’t clog pores or trigger breakouts
- **Free from** parabens, phthalates, sulfites, sulfates, paraffin, petrolatum, formaldehyde & formaldehyde donors, drying alcohol, and synthetic colors
- **Eco-conscious design**: housed in airless capsule, refillable glass bottle
**Full Ingredient List:** Water, Conditioned Media of Human Umbilical Cord Mesenchymal Stem Cells, Hyaluronic Acid, Tropoelastin (sh-Polypeptide-50), Collagen, L-Selenomethionine, L-Proline, L-Cysteine, Xanthan Gum, Sorbitol, Propylene Glycol, Benzyl Alcohol
Free shipping on orders over $450
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#### Exopure Booster with exosomes- The Serum
$400.00
Add to cartSold Out - Notify Me When It’s Available
After 6 Weeks
## Proven Performance
## **92%**
noticed brighter, more luminous skin
## **89%**
said skin looks and feels healthier
## **87%**
felt stronger, more resilient skin
## **87%**
reported a youthful, radiant glow
\*Based on a consumer study after 6 weeks of daily use
[Real results gallery](/content/pages/real-results/index.html)
## Advanced Exosome Technology
Exosomes are microscale messengers released by your cells. Think of them as tiny packages of regenerative signals that tell your skin to heal, repair, and renew itself.
## Triple-Action Regeneration
1. **Cellular Communication** Boosts collagen and elastin by enhancing intercellular signaling—reducing fine lines and improving firmness.
2. **Deep Regeneration** Promotes dermal renewal by replacing damaged skin cells—improving tone, texture, and visibly fading dark spots.
3. **Anti-Inflammatory Healing** Soothes redness, calms irritation, and strengthens the skin barrier for long-term resilience.
Regenera exopure booster serum
## Protocols
Professional skincare integration for prevention, repair, and post-procedure recovery
[See Protocols](/content/pages/exopure-booster-serum-protocols/index.html)
## Find your personalized Regenerative Routine
## preventing aging
Find Your Personalized Regenerative Routine
[Start](/content/pages/your-ritual/index.html)
## targeting damage
Discover how to use Regenera’s Exopure Booster Serum
[Start](/content/pages/your-ritual/index.html)
## recovering from treatment
Match your skin’s unique needs
[start](/content/pages/your-ritual/index.html)
## CONSUMER APPROVED
Backed by regenerative science and confirmed by real users, this potent serum visibly transforms skin's appearance for the long term.
With continued use, users saw a dramatic improvement across key markers of skin health:
- Reduced appearance of fine lines and wrinkles
- Improved firmness and elasticity
- Brighter, more even skin tone
- Smoother texture and soft feel
- Restored radiance
[Shop now](/content/collections/start-your-jouney-today/products/exopure-serum?variant=50587858239817#!/index.html)
[Shop now](/content/collections/start-your-jouney-today/products/exopure-serum?variant=50587858239817#!/index.html)
THE SCIENCE
## Exosomes: Your Skin’s Tiny Messengers
Exosomes are naturally occurring, nano-sized vesicles that carry bioactive signals between cells. In skincare, they help:
- Stimulate collagen and elastin production
- Calm visible inflammation
- Promote balanced, healthy skin function
Our exosomes are derived from ethically sourced human umbilical-cord mesenchymal stem cells (UC-MSCs), obtained with maternal consent. They are **acellular**—containing no nuclei—making them safe for cosmetic use.
Each milliliter of our serum contains approximately **600 million exosome particles**, ensuring consistent potency in every drop.
[All you need to know about Exosomes](/content/pages/the-science/index.html)
THE SCIENCE
## 18 BILLION CELLULAR MESSENGERS
The core of the Exopure serum is an unprecedented concentration of **18 billion MSC-derived exosomes** in every bottle.These are nature's most intelligent microscopic messengers, responsible for facilitating cell-to-cell communication. Ethically sourced from Human Umbilical Cord MSC Conditioned Media, these powerful vesicles are rich in over 500 different growth factors and peptides that signal your skin to begin its natural repair and renewal functions
THE SCIENCE
## 18 BILLION CELLULAR MESSENGERS
not anti-aging
## A VISIBLE LONGEVITY RITUAL
Most products focus on surface-level fixes. We go deeper. Our approach is rooted in skin longevity science—supporting your skin’s ability to stay healthier, stronger, and more resilient over time.
With consistent use, skin looks visibly transformed across three key dimensions:
**\+ Smoothness:** Fine lines and wrinkles appear softened for a smoother, more refined texture.
**\+ Firmness & Volume:** Skin feels plumper and more resilient—restoring youthful bounce and definition.
**\+ Radiance:** Dullness is diminished, revealing a luminous, healthy-looking glow.
This is more than anti-aging—it’s skin longevity. A daily ritual backed by science, designed to help your skin stay youthful longer.
[Explore the science of longevity](/content/pages/science-of-skin/index.html)
## Hero Ingredients
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## Exosomes (MSC-Derived)
_The Regenerative Engine_
Our ethically-sourced Human Umbilical Cord MSC Conditioned Media is the core of our formula. This potent bio-serum is rich in over 500 different growth factors, peptides, and exosomes.
**What It Does:** It provides the essential signals to encourage your skin's natural repair and renewal processes, visibly reducing signs of aging, improving texture, and restoring youthful radiance.
Your browser does not support the video tag.
## Collagen
_The Skin’s Scaffolding_
Collagen is the most abundant protein in your skin, forming the essential framework that provides strength and structure. Our formula includes a bio-available form of collagen that integrates with your skin's surface.
**What It Does:** It helps to reinforce the skin’s foundational matrix, improving structural support from the outside in. This immediate support helps to diminish the appearance of fine lines and wrinkles, promoting a visibly smoother and firmer skin surface.
Your browser does not support the video tag.
## Hyaluronic Acid
_The Hydration Multiplier_
A multi-molecular weight Hyaluronic Acid that hydrates the skin at every level.
**What It Does:** Draws and locks in moisture, instantly plumping the skin to smooth out fine lines and providing deep, lasting hydration.
Full Ingredient List (INCI)
Water, Conditioned Media of Human Umbilical Cord Mesenchymal Stem Cells, Hyaluronic Acid, Tropoelastin (sh-Polypeptide-50), Collagen, L-Selenomethionine, L-Proline, L-Cysteine, Xanthan Gum, Sorbitol, Propylene Glycol, Benzyl Alcohol
## Your Daily Longevity Ritual
## STEP 1
After cleansing, gently pat your face and neck completely dry, preparing the skin for optimal reception.
## STEP 2
Dispense 1–2 pumps of _Exopure Booster Serum, formulated with a high concentration of exosomes_ into fingertips.
## STEP 3
Lightly press the serum along facial pressure points. This gentle motion encourages deep absorption and enhances microcirculation, amplifying the serum's effects.
## STEP 4
Complete the ritual by applying any remaining serum to the neck and décolletage.
_“As a physician, I believe the future of skincare lies in treating the skin as a living organ—one that can be nurtured, repaired, and preserved. At Regenera, we harness the body’s own biological messengers, exosomes, to awaken the skin’s innate capacity for renewal. Our mission is not just to address the signs of aging, but to help skin function at its healthiest for years to come.”_
Lucia Calvisi MD
Co-Founder
Maximum Potency
## Airless Packaging
Crafted with precision, our airless pump system protects the integrity of Regenera Exopure Serum—preserving its bioactive exosomes without the need for added preservatives.
This advanced technology ensures optimal dispensing with every use, so you get the full benefit of the formula—down to the very last drop. Simply pump until no more product is released.
### Your Questions, Answered
Why does Exopure Serum cost $400?
Exopure’s price reflects the **clinical-grade sourcing and safety standards** behind every bottle:
- **Ethical U.S. Sourcing:** Exosomes are derived from **umbilical cord tissue donated in the United States** through fully consented programs.
- **Donor Screening:** Donors are screened following **21 CFR 1271** (U.S. FDA regulations) and **American Association of Tissue Banks (AATB) standards**, including required virology testing for HIV, HTLV, Hepatitis B, and Hepatitis C.
- **Advanced Processing:** Mesenchymal stem cells (MSCs) are carefully cultured, and exosomes are isolated using advanced purification methods for consistency and quality.
- **Potency & Verification:** Each milliliter contains ~ **600 million exosomes**, verified by **Nanoparticle Tracking Analysis (NTA)** to confirm size (30–150 nm) and concentration.
- **Safety Testing:** Every batch undergoes **sterility and endotoxin testing** to ensure purity and stability.
- **Certificate of Analysis:** Each lot is backed by a **COA** documenting particle count, potency, and purity.
This level of **U.S. donor screening, AATB oversight, and biotech-grade lab testing** is what makes Exopure Serum unique—and why it is priced at $400.
How do Regenera exosomes compare to retinol?
Retinol works by promoting exfoliation and cellular turnover, while exosomes represent a next-generation active that signals cellular communication and regeneration. Together, they complement each other—retinol on the surface, exosomes working deeper—helping skin appear smoother, firmer, and more youthful.
What are exosomes, and are they safe for topical use?
Exosomes are naturally occurring **cellular messengers** that help signal skin renewal and cosmetic improvement. Topical **exosome skincare** is considered safe for cosmetic use, and Regenera products undergo **rigorous testing and quality control** to ensure purity, safety, and consistency.
What is the FDA status of exosome skincare?
Currently, no exosome products are FDA-approved for therapeutic use. Regenera Skincare formulations are cosmetics, designed for topical use only. They are not drugs and are not intended to treat or cure medical conditions. All products are manufactured under Current Good Manufacturing Practices (cGMP) to ensure the highest standards of safety and quality.
What is your commitment to transparency and sourcing?
Our exosomes are derived from rigorously screened U.S. human-derived sources, following 21 CFR 1271 and American Association of Tissue Banks (AATB) standards. Each batch is purified with state-of-the-art methods, tested for sterility, potency, and purity, and backed by a Certificate of Analysis (COA). This ensures every bottle delivers biotech-grade quality and consistency.
5\. Can I use Exopure with retinol or vitamin C?
Yes. Apply Exopure Serum first, followed by your retinol or vitamin C serum.
6\. Is it safe for sensitive skin?
Yes. Exopure is dermatologist-tested, oil-free, and suitable for all skin types, including sensitive skin.
7\. How long will one bottle last?
With twice-daily use, a 30ml bottle lasts about 4–6 weeks.
8\. When will I see results?
Most users notice visible improvements within the first week, with optimal results in 4–6 weeks of consistent use.
## All you need
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[Exopure Booster with EXOSOMES- The Serum Travel Size\\
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$280.00](/content/collections/start-your-jouney-today/products/exopure-serum-with-exosomes-travel-size/index.html)
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[Exopure Booster with EXOSOMES- The Serum refill\\
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$320.00](/content/collections/start-your-jouney-today/products/exopure-refill/index.html)
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[Shop Now](/content/products/microneedling-bit-at-home/index.html)
Consumer Testing
⁽¹⁾ Based on a consumer perception self-assessment of 50 participants after using the product for 4 weeks. ⁽²⁾ Based on a consumer perception self-assessment of 50 participants immediately after a single product application.
1 The foundational discoveries that identified and named exosomes occurred in the 1980s. The term "exosome" was first proposed in 1987 to describe small vesicles released from cells.
**Source:** Pan, B. T., & Johnstone, R. M. (1983). Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor. _Cell_, 33(3), 967-977. [https://doi.org/10.1016/0092-8674(83)90040-5](https://doi.org/10.1016/0092-8674(83)90040-5)
2 Exosomes are now recognized as key mediators in regenerative medicine due to their ability to carry therapeutic cargo (proteins, lipids, and nucleic acids) between cells, influencing tissue repair and immune modulation without the need to use whole cells.
**Source:** L. de Abreu, R. C., et al. (2020). Mesenchymal Stromal Cell-Derived Exosomes: A New Therapeutic Paradigm for Regenerative Medicine. _International Journal of Molecular Sciences_, 21(15), 5487. [https://www.mdpi.com/1422-0067/21/15/5487](https://www.mdpi.com/1422-0067/21/15/5487)
3 Studies show that exosomes derived from stem cells can promote tissue regeneration by stimulating cell proliferation, angiogenesis (the formation of new blood vessels), and reducing inflammation in damaged tissues.
**Source:** Ha, D. H., et al. (2020). Mesenchymal stem/stromal cell-derived exosomes for wound healing and regeneration of the skin. _Stem Cells International_, 2020, 9752910. [https://doi.org/10.1155/2020/9752910](https://www.google.com/search?q=https://doi.org/10.1155/2020/9752910&authuser=2)
4 Exosomes function as a sophisticated intercellular communication system. They are released by a "donor" cell and travel to a "recipient" cell, where they fuse with the cell membrane or are internalized, delivering their contents and altering the recipient cell’s behavior and function.
**Source:** Kalluri, R., & LeBleu, V. S. (2020). The biology, function, and biomedical applications of exosomes. _Science_, 367(6478), eaau6977. [https://www.science.org/doi/10.1126/science.aau6977](https://www.science.org/doi/10.1126/science.aau6977)
5 The application of exosome technology in skincare is an emerging and rapidly advancing field. Research has demonstrated that exosomes can enhance skin cell health, for example, by promoting the production of collagen and elastin in fibroblasts, which are critical for skin structure and elasticity.
**Source:** Hu, S., et al. (2019). Human adipose-derived mesenchymal stem cell-derived exosomes promote collagen synthesis and angiogenesis in human dermal fibroblasts. _Scientific Reports_, 9(1), 9432. [https://www.nature.com/articles/s41598-019-45922-2](https://www.google.com/search?q=https://www.nature.com/articles/s41598-019-45922-2&authuser=2)
6 Mesenchymal stem cells (MSCs) are a primary source for therapeutic exosomes. MSC-derived exosomes are particularly valued for their potent regenerative and anti-inflammatory properties, making them a focus for applications in skin rejuvenation and repair.
**Source:** Ferreira, A. D. S., & Gomes, D. A. (2018). Mesenchymal Stromal/Stem Cell-Derived Exosomes in Skin Wound Healing. _Exosomes in Health and Disease_. IntechOpen. [https://www.intechopen.com/chapters/64516](https://www.intechopen.com/chapters/64516)
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